Any truly international IP owner has to keep up-to-date with enforcement developments in the Americas, both North and South. In many areas, form patentability to copyright, the US courts have set standards that have been followed in the region and throughout the world. This year, the Supreme Court has produced two IP-related judgments, which MIP's Americas editor Sam Mamudi analyzes in the introduction. One focuses on the safe harbour for researchers who use patented compounds; the other on the topical issue of music downloads.